Nandrolone D

Ingredients: 
Active ingredient: Nandrolone decanoate; 
1 ml contains 200 mg of nandrolone decanoate; 
Other ingredients: benzyl alcohol, benzylbenzoat, oil peach. 
Pharmaceutical form. Oil solution for injection. 
Pharmacotherapeutic group. Anabolic agents for systemic use. 
ATC code A14A V01. Clinical characteristics. 
Indications. The period of convalescence. 
Anemia due to chronic renal failure. 

Contraindications. 
Hypersensitivity to the drug, prostate cancer, breast cancer in men, breast cancer in women with hypercalcemia, coronary heart disease, pronounced atherosclerosis, nephrotic syndrome, acute and chronic liver disease, including alcoholic disease, nephritis, pregnancy, lactation. 

Dosage and Administration. 
Anemia. 
Adults used intramuscularly: men - 200 mg 1 time per week, women - 100 mg 1 time per week. Therapeutic effect is individual.Treatment should be discontinued in the absence of therapeutic effect after 3-6 months of application. 
After corresponding improvement in blood or normalization should gradually reduce the dose by regularly monitoring the hematologic indices. Declines during dose reduction or after treatment may be an indication to resume treatment. 

The period of convalescence. 
Adults use 50 mg every 3-4 weeks, intramuscularly deep in the muscles. 

Adverse reactions. 
Women - inhibition of ovarian function, menstrual disorders, hypercalcemia. Men - bladder irritation, gynecomastia, priapism, and in old age - hypertrophy and / or carcinoma of the prostate. 
Progression of atherosclerosis, peripheral edema, diarrheal disorders, liver dysfunction with jaundice, changes in the leukocyte formula, pain in the long tubular bones, hypogulation with predisposition to bleeding. 

Overdose. 
Cases of overdose are not were recorded. 
In the case of abuse of drugs containing nandrolone (use larger doses as anabolic product), observed severe endocrine, metabolic and psychiatric adverse reactions. 
Use during pregnancy and lactation. Not used. 
Children. Purpose of the drug is contraindicated for children! 
Precautions. 
Do not exceed recommended dose. 
When prescribing the drug to women should assess the benefits and harm from treatment because of androgenic effect. At the first signs of virtualization in women (coarsening of the voice, hirsutism, acne, klitoromehaliya) should stop taking the drug to prevent irreversible changes. The drug is administered with caution in cardiac dysfunction, hypertension, abnormal liver function and kidney disease, epilepsy, migraine and glaucoma (including history).When treatment is recommended to control intraocular pressure and a possible delay in the body of sodium and water. Maybe suppression factors II, VII, IX and X and increasing blood prothrombin index. 
The change of liver function, so after 4 weeks treatment is recommended to control its functions. Before treatment and then during treatment should be regularly rectal examination prostate. 
In diabetes should review doses antidiabetic drugs. 
With progressive malignant tumors requires correction treatment on the basis of renal trial and the patient. 
Influence on ability to drive a car or operating other machinery. 
No effect. 
Interaction with other medicinal products and other forms of interaction. 
Glucocorticoids, mineralocorticoids, corticotropin, preparations containing sodium and foods rich in sodium, potentiate fluid retention in the body, increase the risk of edema, acne eruptions.Enhances effects antyahrehantiv, indirect anticoagulants, insulin and oral antydiabetychnyh means, coumarin derivatives, weakens - growth hormone and its derivatives. 

Pharmacological properties. 
Synthetic testosterone derivative with a weak androgen, but enhanced anabolic effect. Anabolic effect is activation of reparative processes in the epithelium (coating and glandular), bone and muscle tissues as a result of stimulation of protein synthesis and structural components of cells. Increases complete absorption of amino acids from the small intestine (with diet enriched in proteins), creates a positive nitrogen balance. It stimulates the production of erythropoietin and activates anabolic processes in bone marrow that while appointing iron supplementation does antianemic action. Inhibits the synthesis of endogenous gonadotropins and testosterone. In large doses inhibits spermatogenesis. May delay growth and sexual formation of children. Violates the synthesis of vitamin K-dependent plasma coagulation factors (II, VII, IX, X) in the liver, changes the plasma lipid profile (increased LDL and decreases HDL content), increases the reabsorption of sodium and water in the kidneys, causing the formation of peripheral edema. 

Shelf life. 5 years. 

Storage. Store at temperatures above 25 ° C in a dry place, protected from light and reach of children. 

Packaging. 
1 ml in ampoules, vials and 5 in the cardboard box. 5 ml or 10 ml vials, 1 vial in a cardboard box.